Author/Editor		Ihan, Alojz
Title		Spremljanje imunomodulatornih učinkov s pretočno citometrijo - govorica limfocitnih populacij
Translated title		Following immunomodulatory effects using flow cytometry - the language of lymphocyte subsets
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 43, št. Suppl 5
Publication year		2004
Volume		str. 9-14
Language		slo
Abstract		Flow cytometric analysis of lymphocyte subsets has been used extensively in clinical practice to aid in the diagnosis of various immunological diseases. In this review article, we focus on the use of flow cytometry in the examination of therapeutic response after immunomodulating therapies. During the past years, investigators examined extensively lymphocyte subsets in subjects undergoing immunotherapy of autoimmune and hypersensitive diseases. In many cases it was demonstrated that following lymphocyte subsets during immunotherapy enables better insight into the disease course as well as more rational use of immunotherapeutic drugs.
Summary		Analiza limfocitnih populacij s pretočnim citometrom se v klinični praksi uporablja za diagnostiko različnih imunsko pogojenih bolezni. V članku se omejujemo na uporabo pretočne citometrije za sledenje učinkov imunomodulatornih terapij. Zadnja leta so številni raziskovalci preučevali spremembe limfocitnih populacij pri bolnikih z avtoimunskimi ali preobčutljivostnimi boleznimi, ki so bili zdravljeni z imunoterapevtiki. V številnih primerih so raziskovalci pokazali, da spremljanje limfocitnih populacij med imunoterapijo omogoča boljši vpogled v potek bolezni, hkrati pa omogoča tudi bolj racionano uporabo imunoterapije.
Descriptors		LYMPHOCYTE SUBSETS ADJUVANTS, IMMUNOLOGIC FLOW CYTOMETRY IMMUNOTHERAPY IMMUNOPHENOTYPING HYPERSENSITIVITY AUTOIMMUNE DISEASES