Author/Editor		Jevtič, Vladimir; Majcen, Natalija
Title		Demonstration of evolution of hemispherical spondysclerosis by contrast enhanced Gd-DTPA magnetic resonance imaging
Translated title		Prikaz napredovanja hemisferične spondiloskleroze s slikovno magnetno resonanco in paramagnetnim kontrastnim sredstvom Gd-DTPA
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 38, št. 4
Publication year		2004
Volume		str. 275-84
Language		slo
Abstract		Background. The purpose of the study was to estimate the value of Gd-DTPA magnetic resonance imaging (MRI) in demonstrating the evolution of hemispherical spondylosclerosis (HSS). Patients and methods. In eighteen patients with chronic low back pain and typical radiographic findings of HSS seen on plain films, Gd-DTPA MRI of the lumbar spine was performed. MRI morphological and signal intensity appearances of HSS were analysed and compared with radiographic changes. Results. On the basis of MRI features, three distinct groups of cases were identifiable. Within the first group the region of dome-shaped osteosclerosis demonstrated low signal intensity on T1-weighted precontrast spin-echo images, high signal intensity on T2-weighted images and diffuse contrast enhancement on T1-weighted postcontrast images, findings compatible with bone marrow oedema and hyperaemia. The second group showed high signal intensity vertebral body corners surrounded by low signal intensity area, which indicated the combination of fat accumulation and the sclerotic bone. In the third intermediate group anterior disco-vertebral junctions revealed a mixture of MRI appearances characteristic of the first and the second group. Conclusions. Gd-DTPA MRI is capable of demonstrating a spectrum of features which reflect the evolution of HSS. These typical appearances showed by MRI could be of eventual clinical relevance in following the progression of HSS.
Summary		Izhodišča. Namen študije je bil ugotoviti vrednost slikovne magnetne resonance (MRI) s paramagnetnim kontrastnim sredstvom Gd-DTPA v prikazu napredovanja hemisferične spondiloskleroze (HSS). Bolniki in metode. Pri 18 bolnikih s kronično bolečino v križu in tipičnimi radiografskimi znaki HSS smo opravili Gd-DTPA MRI lumbalne hrbtenice. Primerjali smo morfološke spremembe in spremembe intenzitete signala z radiografskimi znaki HSS. Rezultati. Na podlagi MRI smo primere razdelili v tri skupine. V prvi skupini je bilo radiografsko področje osteoskleroze hipointenzivno na T1-poudarjenih spin-eho slikah, hiperintenzivno na T2-poudarjenih slikah in je kazalo difuzno nabiranje paramagnetnega kontrastnega sredstva. Opisane spremembe so bile združljive s kostnim edemom in hiperemijo. V drugi skupini so bili robovi vretenc na vseh slikovnih sekvencah hiperintenzivni, obdani s hipointenzivno cono in se v njih ni nabiralo kontrastno sredstvo. Opisano je izražalo kombinacijo maščevja in kostne skleroze. Pri preostalih bolnikih so MRI znaki predstavljali kombinacijo sprememb vidnih v prvi in drugi skupini. Zaključki. Gd-DTPA MRI kaže zapletene histološke spremembe v teku napredovanja HSS. Spremljanje značilnih MRI znakov ima lahko klinični pomen pri sledenju bolezni.
Descriptors		SPINAL DISEASES OSTEOSCLEROSIS MAGNETIC RESONANCE IMAGING GADOLINIUM DTPA