Author/Editor		Kališnik, Jurij Matija
Title		Neinvazivna ocena elektrofizioloških lastnosti srca pred premostitveno operacijo koronarnih arterij in po njej
Type		monografija
Place		Ljubljana
Publisher		Univerza v Ljubljani, Medicinska fakulteta
Publication year		2004
Volume		str. 71
Language		slo
Abstract		Objectives Cardiac autonomic modulation (CAM) is deranged in patients after coronary artery bypass grafting (CABG) using cardiopulmonary bypass. This altogether with reperfusion injury after cardiac arrest leads to increased propensity to arrhythmias and higher oxygen consumption worsening patients' recovery after operation. Increased sympathetic activation and hyperadrenergic status after surgically induced endogenous catecholamine release cause postoperative supraventricular arrhythmias. Similarly, the occurrenee of ventricular arrhythmias after CABG is attributed to re-entry mechanisms being enhanced by increased sympathetic tone. Altered ventricular repolarisation may additionally increase proarrhythmic vulnerability. On the other hand, higher vagal CAM may be desired reducing postoperative oxygen consumption, counterbalancing sympathetic activation and thus facilitating the recovery, however, the data relating on- and off-pump CABG, CAM, ventricular repolarisation and the incidence of arrhythmic events other than atrial fibrillation are sparse. We aimed to clarify how the different techniques of CABG affect postoperative CAM, ventricular repolarisation and the incidence of arrhythmic events in supine and right recumbent position. (Abstract truncated at 2000 characters).
Descriptors		CARDIOPULMONARY BYPASS ELECTROCARDIOGRAPHY ARRHYTHMIA HEART RATE INTENSIVE CARE UNITS TACHYCARDIA, ECTOPIC ATRIAL TACHYCARDIA, VENTRICULAR TACHYCARDIA, SUPRAVENTRICULAR ANALYSIS OF VARIANCE PROSPECTIVE STUDIES