Author/Editor		Rajer, Elizabeta
Title		Vpliv športne vadbe na nihanja krvnega sladkorja pri mladostnikih s sladkorno boleznijo
Type		monografija
Place		Ljubljana
Publisher		Univerza v Ljubljani, Medicinska fakulteta
Publication year		2004
Volume		str. 48
Language		slo
Abstract		Background. Regular physical activity is an important part of treatment for patients with type I diabetes mellitus (T1D). It helps in maintaining good metabolic control, delays the onset of cardiovascular diseases and helps to regulate the bodyweight. At the same time, physical activity, especially if not well planned, represents one of the major risk factors for hypoglycemia. The insulin sensitivity of muscle cells remains higher up to 48 hours after physical activity. Patients with T1D on continuous subcutaneous insulin injection (CSII) have less hypoglycemic events in everyday life as compared to their peers on multiple daily injections (MDI). Less data are available on hypoglycemic events in adolescents with T1D on CSII after exercise. Methods. Thirty nine adolescents with T1D agreed to participate in the study. Nineteen of them were on MDI (age 17.2+-3.4 years, GIyHbA1c 8.6+-1.4%, insulin dose 0.75+-0.25 IU/kg, duration of diabetes 6.6+-4.2 years), and 20 were using CSII (age 17.7+-4.5 years, GIyHbA1c 8.1+-1.2%, insulin dose 0.63+-0.14 IU/kg, duration of diabetes 9.3+-4.3 years). On the day 1 of the investigation patients started to follow a fixed regulated diet (2200 kcal/day for females and 2800 kcal/day for males). Continuous subcutaneous glucose monitor (CGMS, Medtronic MiniMed) was installed and the participants were instructed to perform only routine daily activity without any exercise or sport. On the day two at 5 P.M. all participants started with the exercise protocol. After a ten minute warm-up period a 30 minute treadmill exercise programmed at 70% of their calculated maximal physical load, and followed by a 10 minutes cool down period, was performed. Blood glucose was measured before exercise and corrected if determined higher then 14 mmol/l or lower then 6 mmoll. Patients on MDI were instructed to reduce the pre-lunch bolus insulin dose by 10%. (Abstract truncated at 2000 characters).
Descriptors		DIABETES MELLITUS, INSULIN-DEPENDENT EXERCISE INSULIN INFUSION PUMPS, IMPLANTABLE HYPOGLYCEMIA ADOLESCENCE BLOOD GLUCOSE HEMOGLOBIN A, GLYCOSYLATED