Author/Editor		Arslan, Mehmet; Karadeniz, Ahmet N; Aksu, Goerkem; Gueveli, Murat
Title		Cranium eroding sweat carcinoma: a case report
Translated title		Prikaz primera karcinoma znojnih žlez, ki je razjedal lobanjske kosti
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 39, št. 1
Publication year		2005
Volume		str. 55-9
Language		slo
Abstract		Background. Sweat gland carcinomas are rare turnors. Eccrine sweat gland carcinomas are also very rare, with only about 200 cases reported in the world literature and only one of them was eroding the cranium. Treatment modalities of these carcinomas are not well known. Case report. Our patient was 47 years old female. Since 1989, she was operated on six times because o f the tumour relapses. After each operation, the pathological results were: sweat gland adenoma, sweat gland tumour, cylindroma, turban tumour, malign cylindiroma. That was her seventh relapse. On examination, a lesion of the size 10 x 6 cm was observed in the left parietal region. Computed tomography showed the lesion had the size of 11 x 5 cm, and was destroying the tabula externa, diploic region and tabula. The tumour was invading the dura and causing periost reaction. Surgery and postoperative radiotherapy treatment was planned because of malign transformation and risk of recurrence. Conclusians. Only one case with cranium erosion was reported in literature. In our case, also intracranial extension of the tumor was observed.
Summary		Izhodišča. Karcinomi znojnih žlez so redki tumorji. Prav tako so redki tisti karcinomi znojnih žlez, ki so žlezno aktivni. Do sedaj je v literaturi opisanih le okoli 200 primerov in samo eden je razjedal lobanjske kosti. Zaradi njihove redkosti tudi ne poznamo najprimernejšega in najučinkovitejšega zdravljenja. Prikaz primera. Opisujemo 47-letno bolnico, ki so jo po začetni operaciji leta 1989 še šestkrat operirali zaradi ponavljajočega se tumorja v predelu kože kraniuma. Patomorfološki pregled je po vsaki operaciji pokazal benigni tumor (adenom znojne žleze, cilindrom), razen po zadnji, ko smo ugotovili maligni cilindrom. Pred zadnjo operacijo smo ugotovili, da je recidivni tumor, ki je ležal v levi parietalni regiji velik 10 x 6 cm. Z računalniško tomografijo pa smo videli, da je 11 x 5 cm velik tumor poškodoval lobanjske kosti, vraščal v duro ter povzročal periostalno reakcijo. Zaradi maligne transformacije in velike nevarnosti ponovitve bolezni smo se odločili za postoperativno radioterapijo. Zaključki. Do sedaj je ob naši bolnici opisan samo še en primer, kjer je tumor znojnih žlez vraščal v lobanjske kosti.
Descriptors		SWEAT GLAND NEOPLASMS PARIETAL BONE NEOPLASM INVASIVENESS MIDDLE AGE