Author/Editor		Škoberne, Andrej
Title		Sindrom sistemskega vnetnega odgovora pri bolnikih, napotenih v urgentno infektološko ambulanto
Type		monografija
Place		Ljubljana
Publisher		Univerza v Ljubljani, Medicinska fakulteta
Publication year		2004
Volume		str. 34
Language		slo
Abstract		BACKGROUND. Patients with acute infectious or certain noninfectious diseases may develop a systemic inflammatory response syndrome (SIRS). The syndrome is present when at least two of these four criteria are met: a) a body temperature of >38°C or <36°C; b) a heart rate of >90/min; c) a respiratory rate of >20/min or a PaCO2 <4.3 kPa; d) an alteration of the white blood cell count of >12,0x109/L or <4,0x109/L, or the presence of >10% immature (band) neutrophils. Patients with SIRS are in danger of developing sepsis, septic shock and multiple organ dysfunction, due to the ability of the systemic inflammatory response syndrome to interfere with the homeostatic mechanisms of the organism. SIRS criteria may serve as an indicator of the severity of the disease process and could potentially be useful in identifying patients who need inpatient care. AIM. The aim of this study was: a) to establish the presence of SIRS criteria in patients examined under the suspicion of having an infectious disease and b) to establish whether there is a correlation between the presence of SIRS criteria and the need for hospitalization. III'POTHESIS. We assumed that the majority of patients admitted to the hospital would have SIRS and that the percentage of patients with SIRS in the group not admitted to the hospital would be significantly lower than in the group that was admitted. Furthermore we assumed that patients with SIRS who were not admitted to the hospital would be admitted for subsequent hospitalization more frequently than patients without SIRS. METHODS. The study was prospective. Between January 6th 2003 and February 28th 2003, 968 patients over the age of 15, were examined in the emergency room of the Departrnent of Infectious Diseases in Ljubljana and included into the study. Basic demographic data (age, sex) was taken and the presence of SIRS criteria noted. (Abstract truncated at 2000 characters).
Descriptors		SEPSIS SYNDROME EMERGENCIES HOSPITALIZATION ADULT PROSPECTIVE STUDIES