Author/Editor     Han, Ruben; Žagar, Ivana; Mitrović, Svetlana; Bojanić, Predrag
Title     Salivary excretory index - quantification of the ascorbic acid response in dynamic radionuclide sialography
Type     članek
Source     Med Pregl
Vol. and No.     Letnik 46, št. Suppl 1
Publication year     1993
Volume     str. 54-5
Language     eng
Abstract     Dynamic radionuclide sialobgraphy (DRS) provides data about the aptitude of salivary glands to accumulate the tracer and to secrete the saliva. Visual interpretation of the t/a curves may be onerous when salivary glands uptake function is impaired. The purpose of the study has been to quantify the ascorbic acid (AA) response by means of salivary excretion index (SEI). DRS was performed in 10 healthy subjects and in 118 patients with various diseases of the parotid glands. Data acquisition (80 framesl/15 s) started simultaneously with i.v. administration of 99mTcO. Fifteen minutes later AA was given per os. Regions of interest were set over parotid glands. SEI was derived using the formuia: SEI = (2b-a-c)/b. where a,b and c were cpm 3 minutes prior, in the moment when, and 3 minutes after AA was given. In 9 of 10 controls SEI was greater than 55 (mean=63.2). Results in patients with Sjoegren's and Mikulicz's syndrome and sialoadenitis, were sigificantly lower than in healthy subjects. Lowest results were found in patients with sialolithiasis. It may be concluded that SEI improves objective assessment of the AA response particularly in patients with minute or asymmetric disorders of salivarv glands function.
Descriptors     PAROTID DISEASES
ASCORBIC ACID
TECHNETIUM
SALIVATION