Author/Editor     Pituch, Hanna; Rupnik, Maja; Obuch-Woszczatynski, Piotr; Grubešič, Ana; Meisel-Mikolajczyk, Felicija; Luczak, Miroslaw
Title     Detection of binary-toxin genes (cdtA and cdtB) among Clostridium difficile strains isolated from patients with C. difficile-associated diarrhoea (CDAD) in Poland
Type     članek
Source     J Med Microbiol
Vol. and No.     Letnik 54
Publication year     2005
Volume     str. 143-7
Language     eng
Abstract     Clostridium difficile A+B+ and A-B+ strains isolated from stool stamples of patients with C. difficile-associated diarrhoea (CDAD) were selected from the University Hospital Warsaw collection. The binary-toxin genes cdtA and cdtB were detected by PCR in five of the 41 A+B+ strains tested, but in none of the 17 A-B+ strains tested, giving 8.6 % prevalence (5/58) of binary-toxin-positive strains. All of the strains that were positive for binary-toxin genes were grouped into toxitype IV, suggesting that in this institution toxintype IV might dominate among the population of C. difficile with binary-toxin genes.
Descriptors     CLOSTRIDIUM DIFFICILE
BACTERIAL PROTEINS
BACTERIAL TOXINS
CLOSTRIDIUM INFECTIONS
DIARRHEA
POLAND
AGE FACTORS
ENTEROTOXINS
ENTEROCOLITIS, PSEUDOMEMBRANOUS