Author/Editor		Rakar, Stelio
Title		Operativno zdravljenje bolnic z rakom materničnega vratu
Translated title		Surgical treatment of patients with cancer of the cervix uteri
Type		članek
Source		In: Takač I, editor. Mednarodni znanstveni simpozij 50 let Laboratorija za ginekološko citologijo v Mariboru; 2005 jun 17; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2005
Volume		str. 175-80
Language		slo
Abstract		Today not only survival but also the quality of life is an important issue in deciding the surgical treatment of patients with cervical cancer. Attention is paid to preserving organ function and especially reproduction function in young patients. For the choice of treatment of microinvasive cervical cancer we consider a scoring system based on evaluation of morphological criteria (cellular type, mitotic activity, type and depth of stromal invasion, defense reaction, lymphovascular space invasion). In the last period 71% of stage IA cases were treated by conization only. We performed radical abdominal hysterectomy (Wertheim-Meigs-Novak) in patients with localized disease (90% five-year survival) and good general condition. In high risk cases postoperative irradiation is indicated. Most cases of stage IA can be treated conservatively with conization associated in 6-10% with laparoscopic pelvic lymphadenectomy. Even in stage IA2 cases, radical hysterectomy is an "overtreatment ". Radical hysterectomy is the method of choice in stage IB and IIA early disease. T'he radicality of the procedure can be adjusted to prognostic factors in order to avoid long-term postoperative morbidity and preserve good quality of life.
Descriptors		CERVIX NEOPLASMS CARCINOMA, SQUAMOUS CELL NEOPLASM STAGING ADENOCARCINOMA CONIZATION HYSTERECTOMY