Author/Editor		Krunič, Barbara; Sinkovič, Andreja; Marinšek, Martin; Smolle-Juettner, Freya-Maria; Zink, Michael
Title		Primer hude zastrupljenosti z ogljikovim monoksidom, zdravljenje s hiperbarično oksigenacijo
Translated title		A case of severe carbon monoxide poisoning treated by hyperbaric oxygen therapy
Type		članek
Source		In: Hojs R, Krajnc I, Pahor A, et al, editors. Iz prakse za prakso. Zbornik predavanj in praktikum 16. srečanje internistov in zdravnikov splošne medicine z mednarodno udeležbo; 2005 maj 20-21; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2005
Volume		str. 187-92
Language		slo
Abstract		Objectives. Carbon monoxide (CO) poisoning is a major cause of mortality and late neurological sequelae such as memory loss, personality changes, psychosis, dementia, etc. Though the benefit of hyperbaric oxygen (HBO) therapy is still discussed, the majority of trials recommend it in severe cases with coma and/or hemodynamic instability, irrespective of carboxyhemoglobin (COHb) level, to prevent permanent neurological deficits. Methods and results. We present a 35-year-old woman with severe accidental CO poisoning presenting with coma and shock syndrome. After mechanical ventilation with 100% oxygen, IV infusion of IV fluids, dobutamine and noradrenalin, she was transferred to University Hospital Graz for HBO therapy. After treatment she regained consciousness, respiratory failure and shock resolved. She was discharged from our hospital a few weeks later with discrete peroneal paresis, without cognitive disturbances, and she was able to resume her daily activities. Conclusions. In severe CO poisoning, normobaric oxygen therapy and resuscitation by tluids, inotropic agents and catecholamines are essential for survival, but additional H80 therapy seems to prevent major neurological sequelae.
Descriptors		CARBON MONOXIDE POISONING HYPERBARIC OXYGENATION CARBOXYHEMOGLOBIN ADULT