Author/Editor		Žohar-Čretnik, Tjaša
Title		Opredelitev endemskih tipov proti meticilinu odpornega Staphylococcus aureus v Splošni bolnišnici Celje s pomočjo pulzne elektroforeze
Type		monografija
Place		Ljubljana
Publisher		Univerza v Ljubljani, Medicinska fakulteta
Publication year		2005
Volume		str. 96
Language		slo
Abstract		Methicillin-resistant Sfaphylococcus aureus (MRSA) has become a major nosocomial pathogen. Recently many reports on community acquired MRSA were published. Containment of MRSA spread is becoming more important also because of its resistance against glycopeptides. Its epidemiology on different continents, countries, institutions and even wards varies greatly. Development of endemic situation after the initial epidemic spread was successfully prevented only in limited number of healthcare institutions. Surprisingly not much is known about genetic structure of isolates that form endemic state and also about the characteristics of successful strains and clones. In the General hospital Celje (GHC) MRSA had been detected in 1989 for the first time and since 1993 its occurrence has been endemic. For effective prevention of MRSA spread detailed information on genetic structure of MRSA isolates and the dynamics of changes in the population is most needed. The aim of the study was to characterize the predominant MRSA types, their frequency among invasive and non-invasive isolates, changes of structure of MRSA isolates through time and to compare our strains with the representatives of pandemic clones. The results of pulsed field gel electrophoresis (PFGE) typing and antibiogram-resistogram typing results were compared and the usefulness of the latter method was evaluated. (Abstract truncated at 2000 characters)
Descriptors		STAPHYLOCOCCAL INFECTIONS STAPHYLOCOCCUS AUREUS METHICILLIN RESISTANCE ELECTROPHORESIS, GEL, PULSED-FIELD MICROBIAL SENSITIVITY TESTS