Author/Editor		Kanič, Zlatka; Todorović-Guid, Mirjana
Title		Sepsa novorojenčka v enoti intenzivne terapije
Translated title		Sepsis in newborns in intensive care unit
Type		članek
Source		In: Reberšek-Gorišek J, Baklan Z, Kotnik-Kevorkijan B, editors. Nalezljive bolezni v otroški dobi. Zbornik predavanj in praktikum 5. Bedjaničev simpozij z mednarodno udeležbo; 2005 maj 27-28; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2005
Volume		str. 113-8
Language		slo
Abstract		Introduction. Sepsis is one of the main reasons of morbidity and mortalily in newborn and especially in prematurely born. With increased survival in very prematurely born increased treatment intensity and with usage of broad-spectrum antibiotics change in sepsis causative agents is expected. Antibiotic sensitivity in late onset sepsis is expected. Intrapartal usage of antibiotics has increased, hence change in causative agents of early onset sepsis is expected. Patients and methods. Positive haemocltural overview of newborns treated in Clinical department of Paediatrics Maribor in the years 2000 through 2004 has been conducted. Sepsis has been divided in early onset (first 48 hours) and late onset (48 hours after admittance). Positive haemoculture newborns have been divided into 2 groups: (1) haemoculture contamination or transient bacteriemia if patient had no clinical and no biochemical inflammation signs and (2) sepsis, if patient had positive haemoculture with clinical and biochemical inflammation signs. Amongst treated newborns those with clinical sepsis who had clinical and biochemical inflammation response but negative haemocultura have been identified. Results. In the years 2000 through 2004, 939 newborns have been treated, amongst those 498 needed intensive care. Amongst 70 newborns who were septic 121 positive haemocultures were found. Documentation overview found only 100 septic episodes, 21 haemocultures were contaminated. 50 patients had early onset sepsis, amongst them 24 had clinical sepsis, 26 had also positive haemoculture. 79 newborns had late onset sepsis, in 5 cases no causative agent was found. 14 patients died of sepsis. Overall mortality in septic new born was 11, 5%, 14% in early onset and 9% in late onset sepsis. Conclusion. Sepsis is still an important cause of morbidity and mortality in new borns. Although survival of very prematurely born increased, mortality becouse of sepsis did not change.
Descriptors		SEPSIS INTENSIVE CARE UNITS, NEONATAL INFANT, NEWBORN