Author/Editor		Horvat-Ledinek, Alenka; Šega-Jazbec, Saša
Title		Multipla skleroza in nosečnost
Translated title		Multiple sclerosis and pregnancy
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 44, št. Suppl 3
Publication year		2005
Volume		str. 27-30
Language		slo
Abstract		Multiple sclerosis (MS) is the most common chronic inflammatory, demyelinating and autoimmune disease of the central nervous system. It is the most common cause of chronic neurological disability in young adults. MS is more common in women and usually starts in the childbearing period. The number of relapses usually decrease during pregnancy and increase after delivery. Pregnancy does not appear to affect the long term progression of MS. Immunomodulatory and symptomatic treatment of MS is contraindicated during pregnancy and nursing. In the postpartum period, women are treated with intravenous immunoglobulins to reduce the incidence of postpartum relapse.
Summary		Multipla skleroza je najpogostejša kronična vnetna, avtoimunska in demielinizacijska bolezen osrednjega živčevja in eden najpogostejših vzrokov invalidnosti pri mladih ljudeh. Ženske zbolijo pogosteje kot moški, navadno s prvimi simptomi v času načrtovanja družine. V času nosečnosti se ponavadi zmanjša število zagonov bolezni, po porodu pa se verjetnost zagona zveča. Nosečnost ne vpliva na dolgoročni potek multiple skleroze. Imunomodulatorna in simptomatska zdravila, s katerimi zdravimo MS, so v času nosečnosti in dojenja kontraindicirana. Zato bolnice po porodu, da bi zmanjšali verjetnost ponovnega zagona bolezni, zdravimo z imunoglobulini.
Descriptors		MULTIPLE SCLEROSIS PREGNANCY