Author/Editor		Hočevar-Grom, Ada; Veninšek-Perpar, Irena
Title		Spremenjena epidemiologija MRSA v Sloveniji
Translated title		The changing epidemiology of MRSA in Slovenia
Type		članek
Source		In: Berger T, Dobeic M, Vudrag M, editors. Preventiva pred širjenjem zoonoz in drugih nalezljivih bolezni v okolju. Zbornik referatov 2. interdisciplinarni simpozij DDD, zdravje in okolje z mednarodno udeležbo; 2004 okt 22; Ljubljana. Ljubljana: Slovenska veterinarska zveza, Sekcija za DDD in higieno okolja,
Publication year		2004
Volume		str. 62-6
Language		slo
Abstract		Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial infections worldwide. Recent studies suggest that the epidemiology of MRSA may be changing, as the isolation of MRSA is no longer limited to hospitalised patients or persons with predisposing risk factors. These are community acquired MRSA infections (CA-MRSA). These infections have been described among aboriginal population in Australia, outbreaks of CA-MRSA infections in healthy children and adults with no hospital or nursery home contact have been recently described in the United States and Europe in communities such as prison inmates, schoolchildren, i.v.drug users and sport teams. Molecular studies suggests spread of a limited number of PVL-producing MRSA clones that are genetically distinct from hospital-acquired strains. This emergence of PVL+CA-MRSA represents a public health threat, because these strains are associated with severe soft tissue infections and necrotising pneumonia, the latter having a very high case fatality rate (up to 75%). Treatement failure occurs with the betalactam therapy that is usually prescribed for these infections. In our article we are discribing the first reported CA-MRSA outbreak in Slovenia among a group of young healthy persons, members of a sport team, in summer 2004.
Descriptors		STAPHYLOCOCCAL INFECTIONS STAPHYLOCOCCUS AUREUS METHICILLIN RESISTANCE