Author/Editor		Pavlica, Z; Petelin, M; Nemec, A; Eržen, D; Skalerič, U
Title		Vpliv parodontitisa na celotno antioksidantno zmogljivost gingivalne tekočine in seruma pri psih
Translated title		The influence of periodontitis on total antioxidant capacity in gingival crevicular fluid and serum in dogs
Type		članek
Source		Zobozdrav Vestn
Vol. and No.		Letnik 60, št. 3-5
Publication year		2005
Volume		str. 165-74
Language		slo
Abstract		Background: Antioxidant capacity in gingival crevicular fluid and blood serum is correlated to the amount of reactive oxygen species released from activated phagocytes and fibroblasts in inflamed periodontal tissues. Material and methods: The study included 41 miniature poodles. The amount of plaque, degree of gingival inflammation, probing depth and bone loss were assessed in each dog. The antioxidant capacity of gingival fluid was compared to periodontal parameters at the site of gingival fluid sampling, and the antioxidant capacity of serum was compared to periodontal parameters assessed for the whole mouth. Results: Dogs with gingivitis had significantly higher total antioxidant capacity in gingival crevicular fluid, compared to dogs with advanced periodontitis. Total antioxidant capacity in serum was significantly negatively correlated with the degree of gingival inflammation. Conclusion: Inflammation of periodontal tissues affects the antioxidant capacity of serum in dogs. The results of our study suggest that the local delivery of antioxidants may be a useful adjunctive treatment for periodontitis in dogs.
Summary		Izhodišče: Antioksidantna zmogljivost gingivalne tekočine in seruma je povezana s količino reaktivnih kisikovih zvrsti, ki se sproščajo med vnetjem obzobnih tkiv iz aktiviranih fagocitov in fibroblastov. Material in metode: Študija vključuje 41 psov pasme pritlikavi pudelj. Pri vsakem psu smo določili količino mehkih zobnih oblog, stopnjo vnetja dlesne, globino sondiranja in izgubo čeljustne kosti. Antioksidantno zmogljivost gingivalne tekočine smo primerjali s parodontalnimi parametri na mestu njenega odvzema, antioksidantno zmogljivost v serumu pa s parodontalnimi parametri celotne ustne votline. Rezultati: Psi z gingivitisom so imeli značilno višjo celotno antioksidantno zmogljivost v gingivalni tekočini kot psi z napredovalim parodontitisom. Celotna antioksidantna zmogljivost seruma pa se je značilno znižala z napredovanjem vnetja dlesni. Zaključek: Vnetje obzobnih tkiv vpliva na sistemsko antioksidantno zmogljivost pri psih. Rezultati študije nakazujejo možnost dodatnega zdravljenja parodontitisa z lokalnim dovajanjem antioksidantov v obzobne žepe.
Descriptors		PERIODONTITIS DENTAL PLAQUE PERIODONTAL POCKET GINGIVAL CREVICULAR FLUID FREE RADICALS DOGS ALVEOLAR BONE LOSS ANTIOXIDANTS