Author/Editor		Brvar, Miran; Možina, Hugon; Bunc, Matjaž; Možina, Martin
Title		Zdravljenje zastrupitev z zaviralci kalcijevih kanalčkov
Translated title		The treatment of calcium channel blocker poisoning
Type		članek
Source		In: Križman I, editor. Interna medicina 2005: novosti in aktualnosti. Zbornik predavanj 2. kongres Združenja internistov SZD; 2005 okt 21-22; Ljubljana. Ljubljana: Slovensko zdravniško društvo, Združenje internistov,
Publication year		2005
Volume		str. 199-203
Language		slo
Abstract		Calcium channel blockers act in calcium channels so as to prevent calcium influx into cells with resultant decrease in vascular tone and cardiac inotropy, chronotropy and dromotrophy. Poisoning with calcium channel blockers results in reduced cardiac output, bradycardia, atrioventricular block, hypotension and shock. The treatment includes immediate gastric lavage and whole-bowel irrigation in case of ingestion of sustained-release products. All patients should receive activated charoal orally. Specific treatment includes calcium, glucagone and insulin, which proved especially useful in shocked patients. Supportive care, including the use of catecholamines, is not always effective. In case of pharmacological therapy transvenous pacing failure, a balloon pump and cardiopulmonary by-pass may be necessary.
Descriptors		CALCIUM CHANNEL BLOCKERS CALCIUM ANTIDOTES GLUCAGON INSULIN