Author/Editor		Glavač, Damjan
Title		Molecular diagnostics in medicine: the best is yet to come!
Translated title		Molekularna diagnostika v medicini: najboljše šele pride!
Type		članek
Source		In: Luzar B, Poljak M, Glavač D, et al, editors. Molekularna diagnostika v medicini. Zbornik 15. spominsko srečanje akademika Janeza Milčinskega, 36. memorialni sestanek profesorja Janeza Plečnika, 1. srečanje Slovenskega društva za humano genetiko z mednarodno udeležbo; 2005 30 nov - 2 dec; Ljubljana. Ljubljana: Medicinska fakulteta,
Publication year		2005
Volume		str. 95-8
Language		eng
Abstract		The completion of the human genome project and, very recently, the HapMap project accelerate progress in our understanding of the genetic basis of disease, and hence aid the development of new and superior molecular tests. In the coming years, molecular diagnostics will continue to develop and improve. It will facilitate the detection and characterization of disease, as well as monitoring drug response, and will assist in the identification of genetic modifiers and disease susceptibility. Alternative technologies are emerging alongside traditional methodologies such as cytogenetic techniques, in situ hybridization and predominately PCR-based testing. DNA microarrays, highthroughput protein and antibody arrays and the development of integrated chip devices ('lab-on-a-chip') should allow point-of-care testing and facilitate genetic readouts from single cells and molecules. These technologies are enabling the classification of disease, using molecular profiles, as a basis for more effective personalised therapies. Clearly, in the coming years of molecular diagnostics in medicine: the best is yet to come.
Descriptors		CYTOGENETICS POLYMERASE CHAIN REACTION