Author/Editor     Poljšak-Prijatelj, Mateja; Steyer, Andrej; Zimšek-Mijovski, Janet
Title     Molecular diagnostics of gastroenteritis viruses
Translated title     Molekularna diagnostika virusnih gastroenteritisov
Type     članek
Source     In: Luzar B, Poljak M, Glavač D, et al, editors. Molekularna diagnostika v medicini. Zbornik 15. spominsko srečanje akademika Janeza Milčinskega, 36. memorialni sestanek profesorja Janeza Plečnika, 1. srečanje Slovenskega društva za humano genetiko z mednarodno udeležbo; 2005 30 nov - 2 dec; Ljubljana. Ljubljana: Medicinska fakulteta,
Publication year     2005
Volume     str. 387-91
Language     eng
Abstract     Acute gastroenteritis is one of the most common illnesses affecting man and is responsible for significant morbidity and mortality among infants, children and adults worldwide. The annual mortality associated with gastroenteritis has been estimated to be 3.5 to 5 million, with the majority of deaths occurring in developing countries. Acute gastroenteritis is caused by a number of different bacteria, parasites, viruses, toxins and chemicals. The most important viral causative agents are rotaviruses, human caliciviruses (noro-and sapoviruses), enteric adenoviruses and astroviruses. Beside these, coronaviruses, toroviruses, picobirnaviruses, non-group F adenoviruses and picornaviruses have not been found only in the stools of humans with gastroenteritis, but also in healthy individuals. Mixed viral infections have been also detected. Seldom an etiologic agent is found in the specimens tested. The diagnostic gap can be reduced through the use of molecular amplification and detection technique.
Descriptors     GASTROENTERITIS
VIRUS DISEASES
ROTAVIRUS
ADENOVIRIDAE
POLYMERASE CHAIN REACTION
CALICIVIRIDAE