| Author/Editor | Urlep, Darja; Dolinšek, Jernej; Mičetić-Turk, Dušanka | |
| Title | Enteralna prehrana v zdravljenju kronične vnetne črevesne bolezni pri otrocih in mladostnikih | |
| Translated title | Enteral nutrion in the treatment of chronic inflammatory bowel disease in paediatric patients | |
| Type | članek | |
| Source | Gastroenterolog | |
| Vol. and No. | Letnik 9, št. 21 | |
| Publication year | 2005 | |
| Volume | str. 34-9 | |
| Language | slo | |
| Abstract | Inflammatory bowel disease in children and adolescents often causes growth retardation and pubertal delay, the main reasons for them being malnutrition and direct effect of proinflammatory citokines on the linear growth. The growth is additionally sup pressed by antiinflammatory drugs. Crohn's disease and ulcerative colitis are accompanied also by specific nutritional deficiencies, especially of vitamins and minerals. Because of all these reasons, enteral nutrion has a special role in the management of children and adolescents with chronic inflammatory bowel disease. It not only corrects and/or prevents malnutrion and specific nutrition deficits. it is also a part of the primary treatment of Crohn's disease. In patients with intermediate or severe forms of the disease enteral nutrition is as effective as steroids in initiating remission; however causing no side effects is its main advantage over the corticosteroid therapy. | |
| Summary | Kronična vnetna črevesna bolezen, ki se razvije že v otroškem obdobju, pogosto povzroči zaostanek v rasti in spolnem dozorevanju. Glavni vzroki nizke rasti in zapoznelega spolnega razvoja so podhranjenost in neposredno zaviranje linearne rasti, ki ga povzročajo vnetni mediatorji, pa tudi neugodno delovanje protivnetnih zdravil na rast. Crohnovo bolezen in ulcerozni kolitis spremljajo tudi specifični prehrauski primanjkljaji, še posebej pomanjkanje vitaminov in mineralov. Zaradi tega je pri zdravljenju otrok in mladostnikov s kronično vnetno črevesno boleznijo enteralna prehrana zelo pomembna. Preprečuje podhranjenost in specifične prehranske primanjkljaje, pri Crohnovi bolezni pa je tudi del primarnega zdravljenja. Za indukcijo remisije pri zmernih in hudih oblikah bolezni je enako uspešna kot kortikosteroidi. Prednost enteralne prehrane pred zdravljenjem s slednjimi pa je, da nima stranskih učinkov. | |
| Descriptors | INFLAMMATORY BOWEL DISEASES ENTERAL NUTRITION NUTRITION DISORDERS CHILD ADOLESCENCE |