Author/Editor		Derganc, M
Title		Patofiziologija in klinična slika hipoksično-ishemične encefalopatije novorojenčka - kot vodilo za zdravljenje
Translated title		Pathophysiology and clinical picture of hypoxic-ischaemic encephalopathy of the newborn - as a guideline to treatment
Type		članek
Source		In: Burja S, editor. Možgani, ranjeni v zgodnjem razvoju otroka. Zbornik predavanj Mednarodna znanstvena konference Učna delavnica s področja slikovne diagnostike z ultrazvokom; 2005 dec 9-10; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2005
Volume		str. 34-42
Language		slo
Abstract		In the paper we describe the pathophysiology, clinical picture and new methods of treatment of hypoxic-ischemic encephalopathy (HIE) of the newborn. During resuscitation of neonates with HIE, the importance of the prevention of hyperoxia and - during intensive care - of hypocapnia and hyperglycaemia is stressed. In the treatment of HIE promising results have been published on mild to moderate early head and whole body hypothermia. The potential effect of therapeutic hypothermia is also a widening of the therapeutic window for different drugs. Among these erythropoietin seems to be the most promising.
Descriptors		CEREBRAL ISCHEMIA FREE RADICALS REACTIVE OXYGEN SPECIES APOPTOSIS SEVERITY OF ILLNESS INDEX INFANT, NEWBORN