Author/Editor | Sever, Primož; Omejc, Mirko | |
Title | Prognostični pomen zasevkov v bezgavkah pri raku želodca: primerjava nove (5. izdaje) in stare (4. izdaja) TNM klasifikacije raka želodca | |
Translated title | Prognostic value of metastatic lymph nodes in gastric cancer: comparison of new (5th edition) and old (4th edition) TNM classification for gastric cancer | |
Type | članek | |
Source | In: Omejc M, Repše S, editors. Zbornik simpozija Kirurgija želodca - standardi in novosti; 2005 okt 13-15; Ljubljana. Ljubljana: Klinični oddelek za abdominalno kirurgijo, Klinični center, | |
Publication year | 2005 | |
Volume | str. 241-51 | |
Language | slo | |
Abstract | Gastric carcinoma is one of the most common causes of death in malignant diseases of gastrointestinal tract. The TNM classification has become the principal method for assessing the prognosis for cancer patients and to provide a reliable means for reporting and comparing the results of treatments. The 4th edition of TNM classification from the year 1987 was based on the distance of the metastatic nodes from primary tumor. The new 5th edition of TNM classification from year 1997 is based on the number of positive lympho nodes metastases. The study was based on patients who underwent RO resection with appropriate lymphadenectomy and with 15 or more dissected lympho nodes. Many patients classified with old classification were up- and down- staged after they were reclassified with new classification. The study showed, that patients who were in categories pNl and pN2 selected by different criteria in both versions of TNM classification have similar survival probabilities. The advantage of the 5th edition is a new category pN3 with patients with significantly poor prognosis. The 5th edition of TNM classification is better for assessing the prognosis of gastric cancer patients than the 4th edition of classification. The new pN3 group of N category gives 5th edition higher prognostic value and patients are more accurately classified inside of N category. | |
Descriptors | STOMACH NEOPLASMS LYMPHATIC METASTASIS NEOPLASM STAGING PROGNOSIS |