Author/Editor		Rekič, Andreja
Title		Analiza topografije papile vidnega živca pri zdravih osebah s Heidelbergovim tomografom mrežnice in z analizatorjem debeline mrežnice
Translated title		Optic nerve head topography analysis in healthy adults using Heidelberg retina tomograph and retinal thickness analyzer
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 44, št. 4
Publication year		2005
Volume		str. 397-407
Language		slo
Abstract		Optic nerve head topography analysis using the Heidelberg retina tomograph I (HRT) and the Retinal thickness analyzer (RTA) is important in the early diagnosis and follow up of glaucoma. The aims of our research were to obtain our own database for optic disc topography parameters in normal eyes using HRT and RTA, and assess reproducibility of measurements and clinical agreement between both devices. 50 healthy volunteers underwent HRT and RTA examinations of both eyes. To determine reproducibility of measurements 10 volunteers repea ted the examinations of left eyes after a week. Differences between measurements by HRT and RTA were tested for statistical significance. Clinical agreement was assessed with limits of agreement and reproducibility with repeatability coefficient and intraclass correlation coefficient (ICC). Statistically significant differences (p < 0.05) between measurements by HRT and RTA were observed for all parameters, except for rim area (p = 0.051) and height variation contour (p = 0.054). Limits of agreement were wide and clinically important. Repeatability coefficient was good (< 0.10) for all parameters measured by HRT, except for retinal nerve fibre layer (RNFL) cross-sectional area (0.28). Repeatability coefficient was > 0.10 for cup area (0.15), rim area (0.19), maximum cup depth (0.13), height variation contour (0.11), and RNFL cross-sectional area (0.14) measured by RTA. ICC was good (> 90%) for most parameters, except for mean RNFL thickness (89%) measured by HRT and height variation contour (84%) measured by RTA. The two devices cannot be used interchangeably in clinical practice. At present, clinical usefulness of HRT is superior to RTA.
Summary		Analiza topografije papile vidnega živca s Heidelbergovim tomografom mrežnice I (HRT) in z analizytorjem debeline mrežnice (RTA) je pomembna za zgodnje odkrivanje in spremljanje glavkoma. Namen raziskave je bil pridobiti lastne normativne podatke za topografske parametre papile pri zdravih očeh s HRT in RTA ter preveriti ponovljivost in ujemanje med meritvami s HRT in RTA. 50 zdravih prostovoljcev je opravilo preiskavo obeh oči s HRT in RTA. Za določitev ponovljivosti meritev smo pri 10 preiskovancih obe preiskavi po enem tednu ponovili na levem očesu. Preverili smo statistično značilnost razlik med meritvami s HRT in RTA. Ujemanje med aparatoma smo ocenili z določitvijo mej ujemanja. Ponovljivost meritev smo ocenili s koeficientom ponovljivosti in koeficientom korelacije znotraj razreda (ICC). Statistično značilne razlike (p<0,05) med meritvami s HRT in RTA smo ugotovili za vse parametre, razen za površino nevroretinskega obroča (NRO) (p=0,051) in razlike v začrtani meji papile (p=0,054). Meje ujemanja so bile preširoke in zato klinično pomembne. Koeficient ponovljivosti meritev HRT je bil dober (<0,10) za vse parametre, razen za površino prečnega prereza plasti retinalnih živčnih vlaken (PRŽV) (0,28). Koeficient ponovljivosti meritev z RTA je bil >0,10 za površino ekskavacije (0,15), površino NRO (0,15), največjo globino ekskavacije (0,13), razlike v višini začrtane meje papile (0,11) in površino prečnega prereza PRŽV (0,14). ICC je bil visok (>90%) za vse parametre, razen za meritve povprečne debeline PRŽV (89%) s HRT in razlik v začrtani meji papile (84%) z RTA. HRT in RTA nista zamenljiva pri kliničnem delu. Trenutno je HRT bolj uporabna in zanesljiva preiskovana metoda kot RTA.
Descriptors		RETINA OPTIC DISK TOMOGRAPHY MIDDLE AGE AGED