Author/Editor		Medved, Nevio
Title		Pomen konfokalne skenirajoče laserske oftalmoskopije pri diagnosticiranju glavkoma
Type		monografija
Place		Ljubljana
Publisher		Univerza v Ljubljani, Medicinska fakulteta
Publication year		2005
Volume		str. 43
Language		slo
Abstract		Background. Glaucoma defined as progressive optic neuropathy with optic nerve head (ONH) changes and visual field loss in the commonest cause of irreversible blindness in the world. Because central visual acuity is spared till late stages of glaucoma, patients are often asymptomatic. With early detection and treatment of glaucoma, deterioration of visual function can be prevented. Morphology of the ONH is important in the diagnosis and follow up of glaucoma and its changes often precede the onset of visual field defects. In contrast to ophthalmoscopy of the ONH that shows wide variations among different observers, the new imaging devices enable objective and quantitative interpretation of the ONH appearance. In our study, the most frequently used imaging technology, confocal scanning laser ophthalmoscopy with the Heidelberg Retina Tomograph (HRT), was used to evaluate the ONH morphology in healthy subjects and glaucoma patients. Aim. 1) To measure the ONH topographic parameters using HRT in healthy and glaucomatous eyes and to compare our normal data to those from other studies. 2) To evaluate the specificity and sensitivity of ONH evaluation using, the Moorfields regression anaysis (MRA) of HRT in differentiating, normal from glaucomatous eyes. 3) To determine the sensitivity of MRA in detecting glaucomatous eyes with different stages of visual field loss. 4) To establish the correlation between structural measurements of ONH provided by the HRT and visual field indices in glaucoma. 5) To define usefulness of HRT examination in the diagnosis of glaucoma and as a screening test. (Abstract truncated at 2000 characters)
Descriptors		GLAUCOMA OPHTHALMOSCOPY MICROSCOPY, CONFOCAL OPTIC DISK