Author/Editor		Jelenc, Franc; Norčič, Gregor
Title		Operacijsko zdravljenje ulkusa želodca in dvanajstnika
Translated title		Surgical treatment of peptic ulcer disease
Type		članek
Source		In: Repše S, Tonin M, Tomažič A, et al, editors. Zbornik predavanj 41. podiplomskega tečaja kirurgije; 2006 feb 10-11; Ljubljana. Ljubljana: Kirurška klinika, Klinični center,
Publication year		2006
Volume		str. 40-6
Language		slo
Abstract		Background. Perforation and bleeding are the two most common life threatening complications of duodenal and gastric peptic ulcer disease, that require operative treatment. Successful treatment of peptic ulcer disease with H2 receptor antagonists and proton pump inhibitors has reduced the number of elective operative procedures for stenoses: however, the number of operative procedures in elderly patients with perforation and bleeding of peptic ulcer has increased due to concurrent use of NSAID, antithrombotic and anticoagulant drugs. In this group, the incidence of complications and the mortality rate are high. Methods. A retrospective analysis of 184 patients operated between January 2000 and May 2005 at the Department of Abdominal Surgery, University medical Center Ljubljana, due to complications of gastric and duodenal peptic ulcer disease, was made. The group included patients with perforation, bleeding and stenoses. Results. 184 patients were operated, 107 men (58,2%) and 47 women (41,8%). The mean age was 57,9 years for men and 70,9 years for women (p<0,000). The mean age of patients with bleeding was 69,39 years, whereas the mean age of patients with perforation was 61,01 years (p=0,001). 115 (62,5%) patients had duodenal peptic ulcer and 69 (37,5%) patients had gastric peptic ulcer. Indications for operative treatment were: perforation in 113 (61,4%) clases, bleeding in 61 (33,2%) cases and stenosis in 10 (5,4%) cases. Operative procedures were: gastro- or duodenotomy with haemostatic sutures in 151 patients and gastric resection in 25. The most common complications after surgery were respiratory infections and cardiac complications. Overall postoperative mortality was 30,4% (56 patients); mortality was higher in the bleeding group (45,9%, 28 patients) compared to the perforation group (24,8%, 28 patients). (Abstract truncated at 2000 characters)
Descriptors		PEPTIC ULCER PEPTIC ULCER HEMORRHAGE PEPTIC ULCER PERFORATION GASTRECTOMY DUODENAL ULCER AGE FACTORS SEX FACTORS SURVIVAL ANALYSIS RETROSPECTIVE STUDIES