Author/Editor		Wahl, Miloš; Gadžijev, Eldar M; Wahl, Jana; Ravnik, Dean; Pečar, Jani; Pleskovič, Alojz
Title		An experimental model of reproducible liver trauma
Type		članek
Source		Injury
Vol. and No.		Letnik 36, št. 8
Publication year		2005
Volume		str. 963-69
Language		eng
Abstract		The aim of the study was to create an experimental model of reproducible and controllable liver trauma in pigs. The few reported experimental models of liver trauma use the "clamp and crush" mechanism of injury and do not cause reproducible liver injury. In the present study, force was applied through the thoracic wall to mimic a chest injury. Nine pigs were used as experimental animals. In anaesthetised animals, blunt liver trauma was caused with a crossbow using an arrow with a spherical aluminium head as a projectile. Liver injuries of stages II to III according to tiver injury scale were inflicted on all the animals. The stage of liver trauma was proportional to the pressure impulse (ratio between the product of the arrow's mass (m) and the velocity (v) and the contact surface area of the arrow (S)). The presented model of controllable liver injury will enable the study of various aspects of liver trauma since the experiment can be designed in such a way to produce a spectrum of liver injuries.
Descriptors		LIVER DISEASE MODELS, ANIMAL THORACIC INJURIES WOUNDS, NONPENETRATING SEX FACTORS SWINE REPRODUCIBILITY OF RESULTS