Author/Editor		Matela, Jože; Breznik, Silva; Potrč, Stojan
Title		Selektivna embolizacija vene porte kot uvod v kirurško zdravljenje
Type		članek
Source		In: Kozak M, Blinc A, Šabovič M, editors. Žilne bolezni in rak; 2006 apr; Šmarješke toplice. Ljubljana: Združenje za žilne bolezni,
Publication year		2006
Volume		str. 21-5
Language		slo
Abstract		Resection of large hepatocellular carcinoma (HCC) located in the central portion of the liver or in one half of the liver and of diffuse hepatic metastases remains a surgical challenge due to risk of postoperative liver failure. Preoperative portal vein embolization (PPVE) allows physicians to stimulate hypertrophy of the future liver remnant preoperatively, the portion that remains after liver resection. In the period between December 2000 and November 2005, altogether 17 patients underwent PPVE in Maribor general hospital, thereof 10 patients with colorectal metastases and 7 HCC patients. PPVE was performed under general anesthesia. After the indirect splenic portography was performed, the portal vein was punctured percutaneuosly, transhepatic under fluoroscopy. Following portography, selected portal vein segments were embolized by injecting polyvinil alcohol (PVA) particles until stasis of blood flow was achieved. The increase of the remnant liver parenchyma was measured by magnetic resonance imaging (MR) (Toshiba-Visart, 1.5 Tesla) fast T` in tranverse plane. The procedure was technically successful in all except one patient. The volume of the liver parenchyma increased minimally for 4% and maximally for 123%. The results show that PPVE trigger a strong regenerative response resulting in hypertrophy of normal liver parenchyma.
Descriptors		LIVER NEOPLASMS CARCINOMA, HEPATOCELLULAR PORTAL VEIN EMBOLIZATION, THERAPEUTIC