Author/Editor     Vrtovec, Bojan; Stojanovič, Ivan; Radovancevic, Rajko; Yazdanbakhsh, Aria P; Thomas, Cynthia D; Radovancevic, Branislav
Title     Statin-associated QTc interval shortening as prognostic indicator in heart transplant recipients
Type     članek
Source     J Heart Lung Transplant
Vol. and No.     Letnik 25, št. 2
Publication year     2006
Volume     str. 234-6
Language     eng
Abstract     Statin treatment promotes survival after cardiac transplantation by reducing cholesterol levels, allograft rejection, and transplant coronary artery disease. Analysis of data from 114 heart transplant recipients (including 86 treated with statins gor <-1 year post-transplantation) revealed that statins were associated with shortened corrected QT intervals (QTc), reduced low-density lipoprotein cholesterol, and reduced transplant coronary artery disease incidence at 1 year and improved survival at 5 years. Statin-associated QTc shortening thus appears to be a favorable prognostic sign after transplantation.
Descriptors     HEART TRANSPLANTATION
CORONARY DISEASE
ELECTROCARDIOGRAPHY
LIPOPROTEINS, LDL CHOLESTEROL
ANTILIPEMIC AGENTS
SURVIVAL ANALYSIS