Author/Editor     Franko, Artur; Holjar-Erlić, Izidora; Miletić, Damir; Petrović, Oleg
Title     Lhermitte-Duclos disease and pregnancy
Translated title     Lhermitte-Duclosova bolezen in nosečnost
Type     članek
Source     Radiol Oncol
Vol. and No.     Letnik 40, št. 1
Publication year     2006
Volume     str. 17-21
Language     eng
Abstract     Background. Lhermitte-Duclos disease or dysplastic gangliocytoma of the cerebellum is a rare disorder that can cause progressive mass effects to the structures occupying posterior fossa. Magnetic resonance imaging is a diagnostic modality of choice demonstrating characteristic non-enhancing gyriform pattern with the enlargement of cerebellar folia, hypointense on T1 and hyperintense on T2 weighted magnetic resonance images. Case report. The authors present a case of 37-year old woman with previously unknown Lhermitte-Duclos disease in the third trimester of pregnancy from the first signs of the disease to the first six months after delivery. Conclusions. More experience will be needed with this disease in pregnancy and post delivery period to recommend pregnancy for women with such condition. However, this case shows that a pregnant woman with Lhermitte-Duclos disease could reach full-term pregnancy and deliver a healthy child, without lifethreatening risk.
Summary     Izhodišča. Lhermitte-Duclosova bolezen ali displatični gangliocitom malih možganov je redka bolezen, ki lahko povzroča napredujočo tumorsko rast. Ugotovimo jo z magnetno resonanco, ki pokaže značilne neobarvane girusne spremembe, različne intenzitete na T1 In T2 magnetnih slikah. Prikaz primera. Opisujemo 37-letno bolnico, ki smo ji dokazali Lhermitte-Duclosovo bolezen v tretjem tromesečju nosečnosti. Zaključki. Prikazan primer kaže, da lahko nosečnica z Lhermitte-Duclosovo boleznijo brez življenjskega tveganja donosi in rodi zdravega otroka. Potrebnih pa je več izkušenj, da bi to opažanje lahko posplošili.
Descriptors     CEREBELLAR NEOPLASMS
GANGLIONEUROMA
TOMOGRAPHY, X-RAY COMPUTED
MAGNETIC RESONANCE IMAGING
PREGNANCY