Author/Editor     Kralj-Iglič, Veronika; Haegerstrand, Henry; Veranič, Peter; Jezernik, Kristijan; Babnik, Blaž; Gauber, Dorit R; Iglič, Aleš
Title     Amphiphile-induced tubular budding of the bilayer membrane
Type     članek
Source     Eur Biophys J
Vol. and No.     Letnik 34
Publication year     2005
Volume     str. 1066-70
Language     eng
Abstract     Amphiphile-induced tubular budding of the erythrocyte membrane was studied using transmission electron microscopy. No chiral patterns of the intramembraneous particles were found, either on the cylindrical buds, or on the tubular nanoexovesicles. In agreement with these observations, the tubular budding may be explained by in-plane ordering of anisotropic membrane inclusions in the buds where the difference between the principal membrane curvatures is very large. In contrast to previously reported theories, no direct external mechanical force is needed to explain tubular budding of the bilayer membrane.
Descriptors     ERYTHROCYTE MEMBRANE
LIPID BILAYERS
SURFACE-ACTIVE AGENTS
MEMBRANE FLUIDITY
MODELS, CHEMICAL
MODELS, CARDIOVASCULAR
MOLECULAR CONFORMATION
CELL SIZE
CELLS, CULTURED
COMPUTER SIMULATION