Author/Editor | Urbanija, Jasna; Kralj-Iglič, Veronika | |
Title | Giant phospholipid vesicles as a possible diagnostic system for the study of protein interaction with membranes | |
Type | članek | |
Source | In: Elmenreich W, Kaiser H, editors. Proceedings of the Junior scientist conference 2006; 2006 Apr 19-21; Vienna. Vienna: University of technology, | |
Publication year | 2006 | |
Volume | str. 273-4 | |
Language | eng | |
Abstract | The aim of our study is to develop a simple diagnostic tool for detection of certain proteins in a human sera. Phospholipid vesicles are good approximation of real cell membranes, therefore interaction between them and certain proteins of interest (in our case different antibodies and beta2-glycoproteinl) could show the presence of these proteins in the sample. The interactions could be defined by observing the effect of proteins on the morphology and dynamics of vesicles. | |
Descriptors | ANTIPHOSPHOLIPID SYNDROME ANTIBODIES, ANTIPHOSPHOLIPID PHOSPHOLIPIDS IGG ANTIBODIES, MONOCLONAL MICE, INBRED BALB C |