Author/Editor		Chowdhury, Helena H; Zorec, Robert
Title		Patofiziologija debelosti - vloga velikosti adipocita?
Translated title		Pathophysiology of obesity - the role of adipocyte size?
Type		članek
Source		In: Gregorič A, editor. Prepoznava in obravnava duševnih motenj pri otrocih in mladostnikih, dolgotrajni kašelj pri otrocih, obravnava debelosti pri otrocih on mladostnikih na primarni zdravstveni ravni. Zbornik 16. srečanje pediatrov v Mariboru z mednarodno udeležbo in 3. srečanje medicinskih sester; 2006 apr 7-8; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2006
Volume		str. 197-8
Language		slo
Abstract		Obesity refers to the state in which the proportion of fat tissue in the body is above the normal value. Body mass and composition and accumulation of fat are determined by the interaction between genetic, environmental and psychosocial factors, which in the development of obesity, in the final phase, change the energy balance so that the longterm energy intake in the form of food prevails over energy usage. The excess energy accumulates in the form of triglyceride drops in the cytoplasm of adipocytes. In hyperplastic obesity the proportion of fat in the body can increase because of an increase in the number of fat cells. When the proportion of fat increases because of the increase in triglyceride drops in the adipocyte, the fat cells increase in size; this is referred to as hypertrophic obesity. In the adult there is a constant number of fat cells, except in extreme forms of obesity, in which hyperplasia is also seen. The aim of the lecture is to focus on the mechanisms linked with the increased size of adipocytes, what is also the subject of research in our laboratory.
Descriptors		OBESITY ADIPOCYTES CELL SIZE EXOCYTOSIS