| Author/Editor | Šubic, Tjaša; Rozman, Aleš | |
| Title | Ugotavljanje in analiza morebitnih poznih posledic klopnega meningoencefalitisa | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Univera v Ljubljani, Medicinska fakulteta | |
| Publication year | 1997 | |
| Volume | str. 44 | |
| Language | slo | |
| Abstract | Background: Tick-borne meningoencephalitis has been known in Slovenia since World War II. Its incidence is comparatively low, from 5 to 10 cases per 100.000 inhabitants per year. Nevertheless, it is considered a serious health problern since its effects on nervous system may result in permanent disability. The late sequelae of the infection have received little attention in the literature so far, and there have been no reports of further complications appearing after the acute phase of illness. The causative virus closely resembles the poliovirus regarding the pathogenesis and clinical course of the disease. We tried to identify similarities between the two viruses. Aims: We wished to determine whether tick-borne meningoencephalitis might be associated with late sequelae. If so, we wanted to know what they are and whether they progress with time, giving rise to additional complications. The results obtained were compared with changes characteristic of the post-poliomyelitis syndrome. Patients and methods: The study population consisted of 35 patients treated for tick-borne meningoencephalitis 10 years ago, 168 patients treated for the infection 3 years ago and 100 randomly selected subjects who served as controls. Data were gathered with the use of a special questionnaire prepared for study. Same patients were also examined clinically, and the findings were used for assessing the value of the questionnaire-based method. Results: Comparison of the patients treated 3 years ago with the contro group revealed significant diiTerences (p<0.005) for following symptams and signs: fatigue, double vision. dysarthria, tingling and paraesthesias, jaint and muscle pains, freqent headaches, problems with concentration, insornnia and disturbed sleep, depression, irritability, lassitude, increased sweating and intermittent fever. (Abstract truncated at 2000 characters) | |
| Descriptors | ENCEPHALITIS, TICK-BORNE MUSCLE FATIGUE DIPLOPIA ARTHRALGIA HEADACHE ARTICULATION DISORDERS SLEEP DISORDERS DEPRESSION TIME FACTORS QUESTIONNAIRES |