| Author/Editor | Trojar, Andrej; Željko, tadej | |
| Title | Zgodnje funkcijske spremembe levega prekata pri esencialni arterijski hipertenziji | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Univerza v Ljubljani, Medicinska fakulteta | |
| Publication year | 2005 | |
| Volume | str. 47 | |
| Language | slo | |
| Abstract | Background. Essential arterial hypertension (EAFI) is one of the commonest chronic diseases of the circulation system. Early in the development of the hypertension (before the onset of raised blood pressure), the functional and morphological changes of the Ieft ventricle develop. It is most likely that functional changes are earlier and reversible, and they probably precede the development of irreversible morphological changes. Different factors are responsible for morphological changes, especially factors which are part of metabolic syndrome, and aldosterone concentration. Aim. We were interested in functional changes, namely left venlricular diastolic function (LVDF), and possible morphological abnormalities with concomitant biochemical parameters in young normotensive individuals with familial trait (FT) of EAH, who had had functional changes in peripheral arteries detected in the previous study. We also investigated the differences in clinical (body mass index, waist/hip ratio, waist circumference) and biochemical blood parameters (serum conc. of cholesterol, triglycerides, insulin, aldosteron) between FT and control group. The aim of our study was to identify relafionships behveen LV DF and biochemical parameters and evaluate eventual independent correlations between them. Hipotheses. In the rasearch, we tested following hypotheses: T subjects with FT differ from the control group not only in clinical, but also in biochemical parameters, 11 young, healthy, normotensive subjects with FT already have certain functional and probably also morphological changes of left ventricle and left atrium in comparison with the control group, III in the group of young, healthy,normotensive subjects with FT, there are probably correlations between biochemical changes (insulin and aldosterone concentrations) and functional changes of left ventricular function. (Abstract truncated at 2000 characters) | |
| Descriptors | HYPERTENSION VENTRICULAR DYSFUNCTION, LEFT BODY MASS INDEX CHOLESTEROL TRIGLYCERIDES INSULIN BLOOD GLUCOSE ALDOSTERONE ECHOCARDIOGRAPHY |