Author/Editor		Eržen, Barbara; Šabovič, Mišo; Poredoš, Pavel; Šebeštjen, Miran; Keber, Irena; Simčič, Saša
Title		Inflammation markers in young post-myocardial patients exhibiting various expressions of classic coronary risk factors
Type		članek
Source		Coron Artery Dis
Vol. and No.		Letnik 17
Publication year		2006
Volume		str. 325-30
Language		eng
Abstract		Objective We investigated inflammation markers in young post-myocardial infarction patients exhibiting various expressions of classical risk factors. Methods Forty-one male patients with high (n=20) and low (n=21) expression of classical risk factors (risk of coronary events calculated by the prospective cardiovascular Munster study program high or low, respectively), on average 44 years old, who were in the stable phase after myocardial infarction (on average 20.5 months after myocardial infarction) were included in the study. The control group consisted of 25 healthy, age-matched men. The following inflammation markers were measured: leukocyte count, high-sensitive C-reactive protein, interleukin-6, tumor necrosis factor-alpha, intracellular adhesion molecule-1, vascular cellular adhesion molecule-1, selectin-P and selectin-E. Results No differences in the levels of leukocytes, high-sensitive C-reactive protein, tumor necrosis factor-alpha, intracellular adhesion molecule-1, vascular cellular adhesion molecule-1, selectin-P and selectin-E were found between the group of patients and the controls. In contrast, interleukin-6 was significantly (P<0.01) elevated in the group of patients with high (2.5 (1.9-5.3) ng/ml) and low (3.2 (1.5=8.4) ng/ml) expression of risk factors compared with the controls (1.4 (0.9-2.3) ng/ml). Significantly, there was no difference in interleukin-6 between the two groups of patients.
Descriptors		CORONARY DISEASE INFLAMMATION MEDIATORS MYOCARDIAL INFARCTION RISK FACTORS INTERLEUKIN-6 ADULT LEUKOCYTE COUNT C-REACTIVE PROTEIN TUMOR NECROSIS FACTOR CELL ADHESION MOLECULES VASCULAR CELL ADHESION MOLECULE-1 E-SELECTIN P-SELECTIN