Author/Editor		Golle, Andrej; Lorenčič-Robnik, Slavica; Novak, Dušan; Reberšek-Gorišek, Jelka
Title		Odpornost bakterije Pseudomonas aeruginosa in bakterij iz rodu Acinetobacter, osamljenih iz kužnin bolnikov, zdravljenih v Splošni bolnišnici Maribor v obdobju 2001-2005
Translated title		Resistance of Pseudomonas aeruginosa and other bacteria of the Acinetobacter genus isolated from samples of patients treated at the Maribor general hospital during 2001-2005
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 45, št. Suppl 2
Publication year		2006
Volume		str. 39-48
Language		slo
Abstract		In this survey, the objective was to estimate the degree of resistance for Pseudomonas aeruginosa and Acinetobacter spp. isolated from clinical samples of patients from the Maribor General Hospital in the 5-year period from 2001 to 2005. The results of routine susceptibility testing were analysed. Data from intensive care wards were analysed separately. In this analysis, the first isolate per patient per year was used. Degrees of resistance found for the Maribor General Hospital in the 5-year period were as follows: P. aeruginosa: piperacillin 8.5%, piperacillin + tazobactam 15.3%, ceftazidime 4.3%, cefoperazone 8.7%, imipenem 10.9%, meropenem 12.2%, gentamicin 16.5%, amikacin 9.6%, netilmicin 20.7%, tobramicin 18.3% and ciprofloxacin 19.8%; Acinetobacter spp.: piperacillin 55.2%, piperacillin + tazobactam 13.3%, ceftazidime 29.6%, imipenem 1.3%, meropenem 1.9%, gentamicin 43.3%, amikacin 11.0%, netilmicin 39.2%, tobramicin 10.6%, ciprofloxacin 48.9%, ampicillin + sulbactam 3.7%, trimethoprim + sulfamethoxazole 43.5%. Our results are comparable with data from other European countries. However, there are certain differences which indicate the importance of local resistance patterns by which to guide empiric antimicrobial therapy.
Summary		V prispevku smo poskušali oceniti stopnjo odpornosti bakterije Pseudomonas aeruginosa in bakterij iz rodu Acinetobacter, ki smo jih osamili iz kužnin bolnikov iz Splošne bolnišnice Maribor v 5-letnem obdobju od 2001 do 2005. Analizirali smo rezultate vsakodnevnega testiranja občutljivosti. Posebej smo analizirali podatke za oddelke intenzivne nege in terapije. V analizi smo upoštevali le prvi izolat, ki smo ga osamili pri posamičnem bolniku v tistem letu. Stopnja odpornosti za celotno Splošno bolnišnico Maribor za 5-letno obdobje je bila sledeča: za P. aeruginosa: piperacilin 8,5 %, piperacilin + tazobaktam 15,3%, ceftazidim 4,3%, cefoperazon 8,7%, imipenem 10,9%, meropenem 12,2%, gentamicin 16,5%, amikacin 9,6%, netilmicin 20,7%, 39 tobramicin 18,3% in ciprofloksacin 19,8%; za Acinetobacter spp.: piperacilin 55,2%, piperacilin + tazobaktam 13,3%, ceftazidim 29,6%, imipenem 1,3%, meropenem 1,9 %, gentamicin 43,3 %, amikacin 11,0 %, netilmicin 39,2 %, tobramicin 10,6 %, iprofloksacin 48,9%, ampicilin + sulbaktam 3,7%, trimetoprim + sulfametoksazol 43,5%. Naši rezultati so primerljivi s podatki drugih evropskih držav. Opazne so nekatere razlike, ki kažejo, da so lokalni podatki o odpornosti pomembni pri oblikovanju smernic za izkustveno protimikrobno zdravljenje.
Descriptors		PSEUDOMONAS AERUGINOSA ACINETOBACTER DRUG RESISTANCE, MICROBIAL HOSPITALS, GENERAL