Author/Editor     Osredkar, Damjan
Title     Elektroencefalografska metoda povprečevanja amplitud v neonatalni nevrologiji
Translated title     Amplitude-integrated electroencephalography in neonatal neurology
Type     monografija
Place     Ljubljana
Publisher     Univerza v Ljubljani, Medicinska fakulteta
Publication year     2006
Volume     str. 70
Language     slo
Abstract     Monitoring vital signs of newborns, such as heart rate, respiratory rate, and blood pressure, is part of routine care of critically ill newborns, while etectrophysiological monitoring of brain function is not. Brain function can be monitored with amplitudeintegrated electroencephalography (aEEG). Monitoring of newborns with aEEG has been used for assessment of background pattern, detection of seizures, evaluation of the effects of anticonvulsive drugs, selection of patients for neuroprotective intervention, and prediction of neurodevelopmental outcome as early as in the first hours after birth. With the studies presented in this thesis we tried to further etucidate certain aspects of aEEG monitoring of newborns. The aim of the study presented in Chapter 1 was to evaluate the influence of perinatal hypoxia-ischemia on the presence, time of onset, and quality of SWC and identify SWC characteristics that may be of predictive value for neurodevelopmental outcome. The aim of the study presented in Chapter 2 was to assess the time course of recovery of severely abnormal initial aEEG patterns in full term asphyxiated neonates, in relation to other neurophysiological and neuroimaging findings and neurodevelopmental outcome. The aim of the study presented in Chapter 3 was to assess the incidence of postneonatal epilepsy in term infants treated with anticonvulsive drugs for neonatal seizure discharges with or without clinical correlate, that were detected with aEEG.
Descriptors     ASPHYXIA NEONATORUM
CEREBRAL ISCHEMIA
ELECTROENCEPHALOGRAPHY
MAGNETIC RESONANCE IMAGING
EVOKED POTENTIALS, VISUAL
EVOKED POTENTIALS, SOMATOSENSORY
EPILEPSY
INFANT, NEWBORN