| Author/Editor | Ekart, Robert; Hojs, Radovan | |
| Title | Acquired cystic kidney disease and arterial hypertension in hemodialysis patients | |
| Type | članek | |
| Source | Wien Klin Wochenschr Suppl | |
| Vol. and No. | Letnik 118, št. 9-10, Suppl 2 | |
| Publication year | 2006 | |
| Volume | str. 17-22 | |
| Language | eng | |
| Abstract | Background: Acquired cystic kidney disease (ACKD) and arterial hypertension (AH) are both frequent complications in hemodialysis (HD) patients. Until now, AH has not been described as a complication of ACKD. Patients and methods: Our study included 86 HD patients (46 men and 40 women; mean age 51.3 years; mean duration of HD treatment 55.3 months). Their native kidneys were examined with an ATL-HDI 3000 ultrasound device (2-4 MHz convex probe). Depending on the number of cysts in the kidney, the manifestations were divided into three grades: grade 0: no cysts; grade 1: fewer than ten cysts in both kidneys; grade 2: more than ten cysts in both kidneys. Blood pressure was measured 30 minutes before and after HD. Mean one-month values were analyzed. AH was defined as systolic blood pressure >= 150 mmHg, diastolic blood pressure >= 90 mmHg and/or antihypertensive treatment. The diameter of the inferior vena cava (indicator of dry weight) was measured with the same ultrasound device as the kidneys three hours after HD. Results: ACKD was present in 48 (55.8%) patients, there was no statistically significant difference regarding sex. Twenty-four (50%) patients had grade 1 ACKD and 24 (50%) grade 2 ACKD. Sixty-eight (79.1 %) patients suffered from AH, which was significantly more common among the men (P=0.048). AH was detected before HD in 68 (79.1%) patients and in 54 (62.8%) patients also after HD. Thirty-nine (45.3%) patients suffered simultaneously from ACKD and AH; 22 (56.4%) of them were men and 17 (43.6%) women. No significant correlation between AH and ACKD was established. The prevalence and grade of ACKD were significantly associated with the duration of dialysis treatment (P< 0.01). Multiple regression analysis detected a significant correlation only between AH and the diameter of the inferior vena cava (P< 0.05). Conclusions: ACKD is common in HD patients. (Abstract truncated at 2000 characters) | |
| Descriptors | HYPERTENSION HEMODIALYSIS KIDNEY FAILURE, CHRONIC KIDNEY, CYSTIC |