Author/Editor		Potrč, Stojan; Skalicky, Marjan; Ivanecz, Arpad
Title		Does endoscopic ultrasound staging already allow individual treatment regimens in gastric cancer
Type		članek
Source		Wien Klin Wochenschr Suppl
Vol. and No.		Letnik 118, št. 9-10, Suppl 2
Publication year		2006
Volume		str. 48-51
Language		eng
Abstract		Aim: The aim of our study was to evaluate the accuracy of preoperative TNM staging with endoscopic ultrasound (EUS) in gastric cancer patients in comparison with the pathohistological stage of the resected specimen, and to determine the possible implications of EUS for individualized treatment of gastric cancer patients at our institution. Patients and methods: The study included 82 patients operated for resectable gastric cancer between January 1st 2001 and July 1st 2003 at the Maribor Teaching Hospital Department of Abdominal and General Surgery. The EUS stage was assessed preoperatively at the Endoscopical Unit, and the pathohistological stage in the resected specimen was determined postoperatively at the Department of Pathologic Morphology according to recommended standards. Results: Comparison of EUS and pathohistological assessments revealed accuracy of EUS staging for locoregional tumor infiltration (category T) in 68% of patients. The accuracy of EUS staging was 68% for T1, 69% for T2, 69% for T3 and 60% for T4. Lymph nodes (category N) were correctly staged with EUS in 57% of cases. The EUS stage was correct for lymph nodes with no metastases (N-) in 40% of cases, and for lymph nodes with metastases (N+) in 90%. There was no significant difference in accuracy of EUS staging with regard to tumor site (P = 0.768) or tumor size (P = 0.766). Conclusions: According to our results the accuracy of EUS staging matched pathohistological staging with regard to tumor infiltration and lymph node stage in 68% and 57% of cases respectively. Underestimation of the final T2 and T3 stages as T1 stage by EUS presents a problem regarding the consistency of EUS examination at our institution, particularly with respect to individual treatment for early gastric cancer. (Abstract truncated at 2000 characters)
Descriptors		STOMACH NEOPLASMS ENDOSONOGRAPHY NEOPLASM STAGING GASTRECTOMY LYMPHATIC METASTASIS