| Author/Editor | Zidarn, Mihaela | |
| Title | Ponovljivost inspiratorne kapacitete in primerljivost s funkcionalno rezidualno kapaciteto | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Univerza v Ljubljani, Medicinska fakulteta | |
| Publication year | 2006 | |
| Volume | str. 44 | |
| Language | slo | |
| Abstract | Background: For functional diagnosis of pulmonary diseases, lung volume and flow measurements are used. These are especially important in obstructive lung diseases, such as Chronic Obstructive Pulmonary Disease (COPD). Lung volume and flow measurements are used for the diagnosis of COPD, for assessing the severity of the disease, for monitoring disease progression and for assessing the response to bronchodilators. One of the most important COPD symptoms is dyspnea at exertion. Studies have shown that chronic dyspnea does not correlate to lung function assessed with forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). FEV 1 is a weak predictor of exercise tolerance. Bronchodilators are the most frequently used drugs for COPD; but in most patients with COPD, the bronchodilator test is negative if assessed in terms of FEV1. Dyspnea in patients with COPD is related to the level of hyperinflation. Hyperinflation can be assessed with inspiratory capacity (IC). Many studies have shown that IC is reduced in patients with expiratory flow limitation. IC correlates better with chronic dyspnea than FEV1 and FVC, it also correlates better with exercise tolerance than FEV1 and FVC. In patients with expiratory flow limitation, response to bronchodilator is best assessed with IC. IC can be measured with body plethysmography or flow spirometry. Aims: With this study, we wanted to show whether IC measured with flow spirometer is repeatable enough to be used in everyday clinical practice and whether IC can be used instead of FRC to assess dynamic hyperinflation in patients with COPD. The measurement of FRC with body plethysmography is an established method for assessing lung function. The measurement of IC with flow spirometer is much less complicated, but is not used in everyday clinical practice yet. (Abstract truncated at 2000 characters) | |
| Descriptors | LUNG DISEASES, OBSTRUCTIVE SPIROMETRY INSPIRATORY CAPACITY FORCED EXPIRATORY VOLUME FORCED EXPIRATORY FLOW RATES PLETHYSMOGRAPHY, WHOLE BODY TOTAL LUNG CAPACITY RESIDUAL VOLUME FUNCTIONAL RESIDUAL CAPACITY ALBUTEROL |