Author/Editor		Štepec, Srečko
Title		Motnje v nastajanju in strjevanju krvi pri jetrnih boleznih
Type		članek
Source		In: Bricl I, Lampreht N, editors. Zdravljenje s krvjo v gastroenterologiji in hepatologiji. Zbornik strokovnih prispevkov 7. podiplomski seminar Zdravljenje s krvjo; 2005 dec 9-10; Portorož. Ljubljana: Klinični center Ljubljana,
Publication year		2006
Volume		str. 79-84
Language		slo
Abstract		The liver plays an important role in haemopoiesis and synthesis of coagulation proteins: liver disease is associated with a broad range of haematological abnormalities. Anaemia occurs in up to 75% of patients with chronic liver disease. Leucocyte abnormalities range from neutrophilia to neutropenia and lymphopenia. Defects of platelet number and function arise due to the effects of liver disease, immune mechanisms and splenomegalia. Haemostatic abnormalities include impaired synthesis of clotting proteins, synthesis of abnormal clotting proteins, quantitative and qualitative platelet defects and enhanced fibnolytic activity.
Descriptors		LIVER DISEASES ANEMIA THROMBOCYTOPENIA BLOOD COAGULATION FACTORS FIBRINOLYSIS