Author/Editor | Cerar, Vasilij Matko | |
Title | Najnovejša spoznanja o nastanku preeklampsije in njihove posledice v njenem preprečevanju, zgodnjem odkrivanju ter zdravljenju | |
Translated title | Recent advances in the pathogenesis of preeclampsia and their implications in prevention, early detection and therapy | |
Type | članek | |
Source | In: Takač I, editor. Mednarodni znanstveni simpozij 40 let perinatalne medicine v Sloveniji; 2006 jun 16; Maribor. Ljubljana: Splošna bolnišnica Maribor, | |
Publication year | 2006 | |
Volume | str. 273-82 | |
Language | slo | |
Abstract | The author presents recent findings and recognitions regarding the origin of preeclampsia. He describes the disease as genetically grounded maladaptation of pregnant women to the invading trophoblast. The second invasion into spiral arteries of the uterus is hindered. Placental hypoxia causes the release of free radicals, which damage endothelial cell function. The generalized endothelial cell damage causes vasoconstriction in all organic systems of the pregnant woman. There is release of many different proteins and other molecules, which can serve in the detection of the arising disease and its treatment. | |
Descriptors | PREGNANCY COMPLICATIONS PRE-ECLAMPSIA RISK FACTORS PREGNANCY |