Author/Editor		Avčin, Tadej; Tse, Shirley ML; Schneider, Rayfel; Ngan, B; Silverman, Earl D
Title		Macrophage activation syndrome as the presenting manifestation of rheumatic diseases in childhood
Type		članek
Source		J Pediatr
Vol. and No.		Letnik 148, št. 5
Publication year		2006
Volume		str. 683-6
Language		eng
Abstract		We describe 3 patients who presented with features of macrophage activation syndrome (MAS) at the time of presentation of systemic lupus erythematosus (SLE), systemic juvenile idiopathie arthritis, and Kawasaki disease. Immunohistochemical studies in the patient with SLE demonstrated extensive expression of CD163 on hemophagocytic macrophages, suggesting a possible role as a marker of MAS.
Descriptors		LUPUS ERYTHEMATOSUS, SYSTEMIC MACROPHAGE ACTIVATION ARTHRITIS, JUVENILE RHEUMATOID MUCOCUTANEOUS LYMPH NODE SYNDROME ANTIGENS, CD SEX FACTORS INFANT ADOLESCENCE ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC RECEPTORS, CELL SURFACE SYNDROME