| Author/Editor | Franić, Damir | |
| Title | Dejavniki, ki vplivajo na sodelovanje žensk pri nadomestnem hormonskem zdravljenju | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Univerza v Ljubljani, Medicinska fakulteta | |
| Publication year | 2006 | |
| Volume | str. 104 | |
| Language | slo | |
| Abstract | Objectives: To find out the factors influencing women's decision for starting HRT, to stop HRT, as well as to evaluate the influence of educational intervention on the hormone replacement therapy (HRT) continuation rate in Slovenia after the publication of WHI results. Methods: Sixteen Slovenian gynecologists from primary, secondary and tertiary levels, enrolled 125 early postmenopausal women in a 24-month prospective, randomized, controlled, multicentric study. The study group women (n = 62) attended educational lectures; the control group women (n = 63) did not. Data were collected by 2 types of questionnaire: before starting HRT, at follow up visits at 3, 6, 12 and 24 month. The educational lectures were balanced, based on "deductive" and "holistic" approach toward menopausal problems and HRT. The aim was to put the women into decision-making process, so they should decide whether to use of not to use HRT. The conti nuation rate was measured on the basis of women's self-reports. The results were analyzed accor ding to the "intention-to-treat" principle. For comparision of groups, chi square, t-test and Mann Whitney tests were used. The Kaplan-Meier test and Cox proportional hazard model was used for the final (survival analysis. Results: A gynecologist s suggestion, climacteric symptoms and quality of life were the prevailing reasons for starting HRT. The prevailing factors affecting continuation of HRT were: no or irre gular previous OC use (hazard ratio 2.25, no educational lectures (hazard ratio 1.85 climacteric disorders as the reason for start HRT (hazard ratio 1.97, QoL as the reasons for start HRT (hazard ratio 0.51 and friends recommendation (hazard ratio 1.83. In the women who discontinued HRT within the first three months, the fear of endometrial can cer, breast cancer, and bleeding problems were statistically more significant than other factors (p = 0.013). (Abstract truncated at 2000 characters) | |
| Descriptors | MENOPAUSE ESTROGEN REPLACEMENT THERAPY MOTIVATION QUALITY OF LIFE HEALTH EDUCATION SOCIOECONOMIC FACTORS SURVIVAL ANALYSIS QUESTIONNAIRES |