Author/Editor     Writzl, K; Zorn, B; Peterlin, B
Title     Copy number of DAZ genes in infertile men
Type     članek
Source     Fertil Steril
Vol. and No.     Letnik 84, št. 5
Publication year     2005
Volume     str. 1522-5
Language     eng
Abstract     The aim of the study was to define the relevance of deletions and duplications within the DAZ gene cluster to mate factor infertility in a population of 90 infertile men and a control of 50 fertile men using real-time polymerase chain reaction (PCR). We conclude that partial deletions of the DAZ genes are associated with oligozoospermia but not with azoospermia; however, an increased number of DAZ genes does not seem to be a statistically significant risk factor for spermatogenic failure.
Descriptors     INFERTILITY, MALE
GENE DOSAGE
GENE DELETION
RNA-BINDING PROTEINS
MULTIGENE FAMILY
Y CHROMOSOME
GERMANY