Author/Editor | Writzl, K; Zorn, B; Peterlin, B | |
Title | Copy number of DAZ genes in infertile men | |
Type | članek | |
Source | Fertil Steril | |
Vol. and No. | Letnik 84, št. 5 | |
Publication year | 2005 | |
Volume | str. 1522-5 | |
Language | eng | |
Abstract | The aim of the study was to define the relevance of deletions and duplications within the DAZ gene cluster to mate factor infertility in a population of 90 infertile men and a control of 50 fertile men using real-time polymerase chain reaction (PCR). We conclude that partial deletions of the DAZ genes are associated with oligozoospermia but not with azoospermia; however, an increased number of DAZ genes does not seem to be a statistically significant risk factor for spermatogenic failure. | |
Descriptors | INFERTILITY, MALE GENE DOSAGE GENE DELETION RNA-BINDING PROTEINS MULTIGENE FAMILY Y CHROMOSOME GERMANY |