Author/Editor		Stražar, Klemen; Coer, Andrej; Antolič, Vane
Title		Biological impact of polyacetal particles on loosening of isoelastic stems
Type		članek
Source		Biomacromolecules
Vol. and No.		Letnik 7, št. 9
Publication year		2006
Volume		str. 2507-11
Language		eng
Abstract		The aim of our study was to identify biological factors responsible for premature loosening of polyacetal hip stems. The results of histological analyses of the tissue around 11 total hip prostheses with loosened polyacetal femoral stems were compared to those obtained in a group of 11 total hip prostheses with loosened metal (CoCr) femoral components. A higher number of polymer wear particles surrounded by giant cells, more bone chips, and a more extensive necrosis were found around loosened polyacetal stems. Histomorphological characteristics of polyacetal wear particles containing BaSO(4) granules in the tissue around loosened polyacetal stems were described. Radiological evaluation of the wear of polyethylene cups suggested that elastic modulus of the stem had no influence on the wear of polyethylene cups. This study indicates that polyacetal wear particles have a great biological potential accelerating the process of loosening.
Descriptors		HIP PROSTHESIS PROSTHESIS FAILURE CHROMIUM ALLOYS POLYMERS HIP JOINT GIANT CELLS, FOREIGN-BODY BARIUM SULFATE