Author/Editor		Franko, Alenka; Dolžan, Vita; Arnerić, Niko; Dodič-Fikfak, Metoda
Title		Vpliv polimorfizmov metabolnih genov GSTM1 in GSTT1 na tveganje za razvoj azbestoze
Translated title		The influence of metabolic gene polymorphismy GSTM1 and GSTT1 on the risk for development of asbestosis
Type		članek
Source		In: Strokovno gradivo 7. mednarodna konferenca Globalna varnost 2006: za večjo varnost pri delu in v cestnem prometu; 2006; Bled. Ljubljana: Planet GV,
Publication year		2006
Volume		str. 311-4
Language		slo
Abstract		It is known that gene-environment interactions have an important influence on the development of the diseases. Although asbestos-related diseases are among the most extensively studied occupational diseases and the causal relationship between asbestos exposure and asbestosis has been well established, relatively little is known about the genetic factors that might modify the individual susceptibility to the development of this disease. The aim of this study was to select from a cohort of workers occupationally exposed to asbestos a group of subjects for a nested case-control study that would allow us to investigate if the genetic polymorphism of glutathione S-transferases represents a risk factors for the development of asbestosis.
Descriptors		ASBESTOS ASBESTOSIS GLUTATHIONE TRANSFERASES OCCUPATIONAL EXPOSURE POLYMORPHISM (GENETICS) POLYMERASE CHAIN REACTION