Author/Editor		Andoljšek, Dušan
Title		Testi za oceno funkcije trombocitov: novosti
Translated title		In vitro assays for evaluating platelet function: advances
Type		članek
Source		In: Križman I, editor. Interna medicina 2006: novosti in aktualnosti. Zbornik predavanj strokovnega sestanka Združenja internistov SZD, 2006 sep 29-30; Ljubljana. Ljubljana: Združenje internistov SZD,
Publication year		2006
Volume		str. 53-6
Language		slo
Abstract		Assays for platelet function monitor the response of platelets to an agonist or biochemical changes which occur when they are activated. Bleeding time and its modifications, closure time I'FA-100 analyser and platelet agregation studies are in the first group of tests. Biochemical changes upon platelet activation can be measured in different ways, e.g. using monoclonal antibodies and ELISA or flow cytometry. Changes in platelet biochemistry are not necessarily reflected in changes in platelet function. Research is in progress to find the best method for monitoring the safety and efficacy of antibodies and drugs which interfere with GP IIb/IIIa.
Descriptors		HEMOSTASIS PLATELET FUNCTION TESTS PLATELET ACTIVATION