| Author/Editor | Bunc, Matjaž; Starc, Radovan | |
| Title | Unusual causes of acute myocardial infarction: a report on two cases | |
| Translated title | Neobičajni vzroki akutnega miokardnega infarkta: prikaz dveh kliničnih primerov | |
| Type | članek | |
| Source | Slov Kardiol | |
| Vol. and No. | Letnik 3, št. 2 | |
| Publication year | 2006 | |
| Volume | str. 160-3 | |
| Language | eng | |
| Abstract | In most cases acute myocardial infarction (AMI) is the result of complications on atherosclerotically affected coronary arteries (CA). However, AMI may also occur when the CA are normal or nearly normal. In that case the formation of thrombus and coronary spasm should be the leading causes of ischemic events. There are some triggers of coronary artery spasm such as exercise, cold, hyperventilation, alkalosis and drugs such as methacholine, epinephrine, ergot alkaloids, thromboxane A2, cigarette smoking and alcohol. In our case reports we present of a 47-year-old man without atherosclerotic changes on CA who developed AMI after alcohol intoxication, and a 38-year-old man with intact CA who suffered AMI after vigorous exercise are presented. Both case reports are illustrative and could contribute to further clinical evaluation of the mechanisms of AMI. | |
| Summary | V večini primerov je akutni miokardni infarkt posledica zapletov na aterosklerotično spremenjenih koronarnih žilah. V določenih primerih akutnega miokardnega infarkta pa pomembnih zožitev na koronrnih žilah ni moč dokazati. V teh primerih je precej verjeten razlog ishemije ali prehodna tvorba tromba ali pa stisnjenje koronarnega žilja (spazem). Poznani so določeni sprožilni dejavniki skrčenja koronarnih žil: telesni napor, mraz, hiperventilacija, alkaloza, učinki nekaterih zdravil, učinki tobaka, akohol. Prikazujemo primer akutnih miokardnih infarktov pri 47-letnem in 38-letnem moškem z normalnima koronarogramoma. Pri prvem je bil akutni miokardni infarkt lahko povezan z intoksikacijo z alkoholom, pri drugem pa z prekomernim telesnim naporom. | |
| Descriptors | MYOCARDIAL INFARCTION ALCOHOLIC INTOXICATION EXERTION CORONARY VASOSPASM ADULT |