Author/Editor		Blazina, Jerca; Kern, Izidor; Požek, Igor; Vidmar, Stanko
Title		Pljučni hamartom
Translated title		Pulmonary hamartoma
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 75, št. 11
Publication year		2006
Volume		str. 713-7
Language		slo
Abstract		Background Hamartomas are the most common benign neoplasms of the lung. The population incidence is 2.5/1000. In most cases the diagnosis is based on computed tomography (CT) and fine needle aspiration biopsy (FNAB). In this report we reviewed cases of pulmonary hamartoma seen at Golnik Hospital and studied the diagnostic and therapeutic procedures used in each case. Methods 35 cases diagnosed as pulmonary hamartoma at Golnik Hospital in the last eight years were studied. We reviewed medical records of 30 patients who were hospitalized. We also reviewed the cytologic smears of 31 patients. Results There were 21 females and 14 males, the average age was 60.5 years, the average size of hamartoma was 21.7 mm. For diagnosing hamartoma we used CT and FNAB in 16 (45.7%) patients, only FNAB in 15 (42.9% and only CT in 4 (11..4%) patients. Cytologic smears of all 31 patients contained chondroid substance or mature cartilage, fibromyxoid material was present in 29 (93.5%), adipose cells or tissue in 24 (77.4%) and cuboidal cells in 28 (90.3%) specimens. Over this period 6 (17.1%) patients underwent surgery, the definitive histologic diagnosis in all cases was hamartoma. Conclusions In some cases of pulmonary hamartoma the definitive diagnosis can be made only by CT without invasive diagnostic procedures. Many times CT does not yield a definitive diagnosis and in these cases we recommend transthoracic FNAB.
Summary		Izhodišča Hamartom je najpogostejši benigni pljučni tumor. Incidence v splošni populaciji je 2,5/1000. Diagnozo največkrat postavimo z računalniškotomografskim slikanjem (CTS prsnega koša in citološko preiskavo vzorca, dobljenega s transtorakalno tankoigelno aspiracijsko biopsijo (TIAB). Namen raziskave je bil zbrati podatke o vseh bolnikih s pljučnim hamartomom, ki so bili obravnavani v bolnišnici Golnik, in preučiti diagnostične in terapevtske pristope, ki so bili uporabljeni v njihovi obravnavi. Metode Poiskali smo podatke o 35 bolnikih, ki so bili v zadnjih osmih letih odpuščeni iz bolnišnice Golnik z diagnozo hamartom. Pregledali smo popise bolezni tistih 30, ki so bili bolnišnično obravnavani. Ponovno smo pregledali citološke preparate transtorakalnih TIAB, ki so bile opravljene pri 31 bolnikih. Rezultati Razmerje med moškimi in ženskami je bilo 2:3, povprečna starost ob odkritju 60,5 leta, povprečna velikost hamartoma 21,7 mm. Pri 16 (45,7%) bolnikih sta bili v diagnostičnem postopku opravljeni tako CT kot citološka preiskava, pri 15 (42.9%) le citološka, pri 4 (11.4%) le CT preiskava. V citoloških preparatih vseh 31 bolnikov je bil prisoten hrustanec, vezivo v 29 (93,5%), maščoba v 24 (77,4%) in kubični epitel v 28 (90.3%) vzorcih. Izmed 35 bolnikov je bilo v tem času zaradi hamartoma operiranih 6 (17.1%) bolnikov, pri vseh je bila končna histološka diagnoza hamartom. Zaključki V določenih primerih lahko že samo s CT preiskavo prsnega koša tako natančno opredelimo spremembo, da invazivnejša diagnostika ni potrebna. Zaenkrat pa je pri večini bolnikov potrebno opraviti še TIAB ter citološko preiskavo dobljenega materiala. Operativna odstranitev je redko potrebna.
Descriptors		LUNG DISEASES HAMARTOMA TOMOGRAPHY, X-RAY COMPUTED BIOPSY, NEEDLE