Author/Editor		Kecman, Dejan; Jagodnik, Robert
Title		Vpliv hiperlipidemije na sestavo možganskih sterolov pri laboratorijskih miškah C57BL/6
Translated title		Influence of chronical hyperlipidemia on structure of cerebral sterols of laboratory mice C57BL/6
Type		monografija
Place		Ljubljana
Publisher		Srednja vzgojiteljska šola in gimnazija Ljubljana
Publication year		2005
Volume		str. 32
Language		slo
Abstract		Chronical Hyperlipidemia leads to cardiovascular diseases that are a common cause of death in modern world. The reason for these diseases is interruption of cholesterol homeostasis that can be a result of genetical and/or environmental disturbances. Recent studies show that hyperlipidemia is closely connected to neurodegenerative diseased such as Alzheimer's disease. Studies on the model animals indicated that lipid enriched diet lead not only to increase of serum cholesterol but also to increase of cerebral cholesterol. The purpose of our research was to define the amount of cholesterol and intermediates of cholesterol biosynthesis in brains of control and poloxamer P-407 hyperlipidemic mice.
Descriptors		HYPERLIPIDEMIA BRAIN CHEMISTRY CHOLESTEROL STEROLS CHROMATOGRAPHY, HIGH PRESSURE LIQUID MICE, INBRED C57BL